By Nages Nagaratnam, Kujan Nagaratnam, Gary Cheuk

This ebook presents a accomplished review of the 2 vital concerns in terms of ailment in aged: the age-related alterations and the pathophysiology of the illnesses. The publication comprises 19 chapters which are prepared by way of organ process and dependent to hide the categorical parts for a fast yet in-depth figuring out of illnesses in getting older sufferers. not like the other ebook out there, this article is concise and but thorough in method of the stipulated parts. This e-book comprises multiple-choice questions that strengthen the ideas which are most crucial to realizing and treating geriatric sufferers, making it an excellent source by itself or as a significant other to bigger geriatric texts.

Diseases within the aged is the last word source for geriatricians, scientific scholars, fundamental care physicians, sanatorium medical professionals, geriatric nurses, and all different doctors treating and diagnosing illnesses in aged patients.

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107. Mehta JL, Saldeen TGP, Rand K. Interactive role of infection inflammation and traditional risk factors in atherosclerosis and coronary artery disease. J Am Coll Cardiol. 1998;31:1217–25. 108. Nagaratnam N. Toxoplasmosis and heart disease. J Natl Sci Coun Sri Lanka. 1974;2(2): 115–27. 109. Nagaratnam N, Siripala KA. Myocardial toxoplasmosis. Cardiology. 1970;55:272–80. 110. Nagaratnam N, Stephen SJ. Chronic constrictive pericarditis associated with toxoplasmosis. Br Heart J. 1973;35:868–70.

North BJ, Sinclair DA. The intersection between brain and cardiovascular disease. Circ Res. 2012;110:1097–108. 14. Nassimiha D, Aronow WS, Ahn C, Goldman ME. Association of coronary risk factors with progression of valvular aortic stenosis in older persons. Am J Cardiol. 2001;87:1313–4. 15. Lakatta EG, Yin FCP. Myocardial aging: functional alterations and related cellular mechanisms. Am J Physiol. 1982;242:H927. 16. Pugh KG, Wei JV. Clinical implications of physiological changes in the aging heart.

Valvular Disease in the Elderly • Calcific aortic valve disease is not a consequence of ageing, now considered an active process akin to atherosclerosis with chronic inflammatory cell infiltration, active calcification of the leaflets and lipoid deposition [115–117]. • Aortic valve sclerosis is perhaps antecedent to aortic valve stenosis. • Common cause of aortic regurgitation is isolated severe AR from aortic root/annular dilatation [112]. • Types of mitral regurgitation in the elderly are degenerative and result from myxomatous degeneration, primary floppy valves, calcified mitral annulus and ischaemic [127].

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