By Robert Weaver

Molecular Biology, 4/e by means of Robert Weaver, is designed for an introductory direction in molecular biology. Molecular Biology 5/e specializes in the basic innovations of molecular biology emphasizing experimentation. specifically writer, Rob Weaver, specializes in the research of genes and their actions on the molecular point. throughout the mixture of fine illustrations and transparent, succinct writing scholars are awarded primary molecular biology thoughts.

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But when the virus infects a host cell, it seems to come to life. Suddenly the host cell begins making viral proteins. Then the viral genes are replicated and the newly made genes, together with viral coat proteins, assemble into progeny virus particles. 4 Physical Chemistry of Nucleic Acids their behavior as inert particles outside, but life-like agents inside their hosts, viruses resist classification. ” Others prefer a label that, although more cumbersome, is also more descriptive of a virus’s less-than-living status: infectious agent.

Watson, 1968, Atheneum Press, NY. © Cold Spring Harbor Laboratory Archives. (b) Courtesy Professor M. H. F. ) more than one polypeptide chain, whereas a gene has the information for making only one polypeptide chain. (2) Many genes contain the information for making polypeptides that are not enzymes. (3) As we will see, the end products of some genes are not polypeptides, but RNAs. A modern restatement of the hypothesis would be: Most genes contain the information for making one polypeptide. This hypothesis is correct for prokaryotes and lower eukaryotes, but must be qualifi ed for higher eukaryotes, such as humans, where a gene can give rise to different polypeptides through an alternative splicing mechanism we will discuss in Chapter 14.

19 shows a direct, linear relationship between GC content and density, as measured by density gradient centrifugation in a CsCl solution (see Chapter 20). Part of the reason for this dependence of density on base composition seems to be real: the larger molar volume M. phlei Serratia 60 E. coli Calf thymus 40 Salmon sperm S. 19 Relationship between the GC contents and densities of DNAs from various sources. AT-DNA is a synthetic DNA that is pure A + T; its GC content is therefore zero. (Adapted from P.

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