By Frank Dickens, Eric Neil

Oxygen within the Animal Organism is a compilation of papers awarded throughout the symposium on Oxygen within the Animal Organism, together subsidized by means of the foreign Union of Biochemistry and the foreign Union of Physiological Sciences, held at Bedford university, London in September 1963.

The booklet presents a multidisciplinary method of the research of the topic of oxygen within the animal organism. The papers provided hide quite a lot of evidence and hypotheses at the topic. issues mentioned contain experiences within the delivery of oxygen; the basic physics and chemistry of oxygen; the diffusion of oxygen from the capillaries to the mitochondria; the neural and humoral parts to the rules of air flow; and the evolution of biochemical pathways for oxygen.

Biologists, biochemists, biophysicists, physiologists, and researchers will locate the textual content informative and insightful.

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Additional info for Oxygen in the Animal Organism. Proceedings of a Symposium Held Under the Joint Auspices of the International Union of Biochemistry and the International Union of Physiological Sciences, London, 1963

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F. CULLIS, H . MUIRHEAD, M. F. PERUTZ, M. G. ROSSMAN and A. C. T. N O R T H , Proc. Roy. Soc, A 265, 161 (1961). 38A. E. ANTONINI, J. WYMAN, M. BRUNORI, E. BUCCI, C. FRONTICELLI, and A. Rossi- 39. 40. 41. 42. 43. 44. FANELLI, / . Biol. , 238, 2950 (1963). N . U. MELDRUM and F. J. W. ROUGHTON, / . , 80, 143 (1933). H. CONSTANTINE, L. Rossi and F . J. W. ROUGHTON, Proc. Physiol. Soc, July 1963. In the press. L. Rossi and F . J. W. ROUGHTON, / . , 167, 15 P (1963). F . J. W. ROUGHTON, Techniques of Organic Chemistry, Eds.

I. Academic Press, New York (1957). I. E. GRAY, Biol. Bull. 107, 219 (1954). A. A. GREEN and R. W. ROOT, Biol. 10, 274 (1933). F. G. HALL, D . B. DILL and E. S. G. BARRON, / . Cell, and Comp. Physiol. 8, 301 (1936). E. H. HAZELHOFF, Z. vergleich. Physiol. 26, 306 (1938). L. J. HENDERSON, Blood Study in General Physiology. New Haven, Conn. (1928). G. M. HUGHES and G. SHELTON, Respiratory Mechanisms and their Nervous Control in Fish. Advances in Comparative Physiology and Biochemistry. Academic Press, New York (1962).

This theory accounts semi-quantitatively for the new results so far observed, but in order to put it on a firmer basis it is necessary to have more accurate determinations of HbNHCOO ", 0 2 HbNHCOO " and of the constants Kc and Kz for human Hb and 0 2 Hb. Fuller work is currently being devoted to this end. Further studies are also necessary in regard to the possible combination of HCO$ ions with Hb and 0 2 Hb, and the magnitude of the role such combinations may play under physiological conditions.

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